Keratitis caused by the recently described new species Aspergillus brasiliensis: two case reports
نویسندگان
چکیده
INTRODUCTION Human infections caused by Aspergillus brasiliensis have not yet been reported. We describe the first two known cases of fungal keratitis caused by Aspergillus brasiliensis. CASE PRESENTATIONS A 49-year-old Indian Tamil woman agricultural worker came with pain and defective vision in the right eye for one month. Meanwhile, a 35-year-old Indian Tamil woman presented with a history of a corneal ulcer involving the left eye for 15 days. The fungal strains isolated from these two cases were originally suspected to belong to Aspergillus section Nigri based on macro- and micromorphological characteristics. Molecular identification revealed that both isolates represent A. brasiliensis. CONCLUSION The two A. brasiliensis strains examined in this study were part of six keratitis isolates from Aspergillus section Nigri, suggesting that this recently described species may be responsible for a significant proportion of corneal infections caused by black Aspergilli. The presented cases also indicate that significant differences may occur between the severities of keratitis caused by individual isolates of A. brasiliensis.
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Keratomycosis is the most important cause of ocular morbidity which is mainly occurred in field worker as an occupational disease. Fungal keratitis is caused by yeast and filamentous fungi. Aspergillus and Fusarium species are the most prevalent filamentous cause of keratomycosis. The most common yeast cause is Candida species especially C. albicans. In the last reports, trauma to the cornea...
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